It is an old maxim of mine that when you have excluded the impossible, whatever remains, however improbable, must be the truth.
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As a rule, said Holmes, the more bizarre a thing is the less mysterious it proves to be. It is your commonplace, featureless crimes which are really puzzling, just as a commonplace face is the most difficult to identify.
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There is nothing more unaesthetic than a policeman.
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From a drop of water a logician could infer the possibility of an Atlantic or a Niagara without having seen or heard of one or the other.
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When a doctor does go wrong he is the first of criminals. He has nerve and he has knowledge.
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A man should keep his little brain attic stocked with all the furniture that he is likely to use, and the rest he can put away in the lumber-room of his library, where he can get it if he wants it.
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We can't command our love, but we can our actions.
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Our ideas must be as broad as Nature if they are to interpret Nature.
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For strange effects and extraordinary combinations we must go to life itself, which is always far more daring than any effort of the imagination.